Welcome!
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Monash Macromolecular Crystallisation Facility is an automated platform for the high throughput crystallisation of biological macromolecules, operating on a fee-for-service model.
We provide Monash researchers with access to the newest nano-volume crystallisation and imaging technologies using state-of-the-art equipment:
• NT8 (Formulatrix) and
• Mosquito (TTP Labtech) - nano drop dispensing
• Formulator (Formulatrix) - building and dispensing customised optimisation screens using microfluidic technology
• 4 Rock Imagers (Formulatrix) - plate incubators/automated imaging systems
• 2 SONICC crystal detectors (Formulatrix) - using Second Harmonic Generation (SHG) and Ultraviolet Two-Photon Excited Fluorescence (UV-TPEF) for protein crystals detection in sitting drops and LCP
• Prometheus (NanoTemper) - nano DSF – protein thermal unfolding, chemical denaturation and aggregation
Our Services:
• Nano-volume crystallisation screening (vapour diffusion and LCP), followed by automated imaging with remote access to images
• Seeding and additive screening
• Custom screen design and dispensing for optimisation of crystallisation conditions.
• Pre-crystallisation sample evaluation by Differential Scanning Fluorimetry
Jamie Rossjohn
Prof/Director
Danuta Maksel
PhD/Manager
Geoffrey Kong
PhD/Senior Technical Officer
| Hours | Location |
|
Monday-Friday 9:00am-5:00pm |
11 Chancellors Walk Monash University, Clayton Campus |
| Name | Role | Phone | Location | |
|---|---|---|---|---|
| Danuta Maksel, Geoffrey Kong |
99059777
|
mmcf@monash.edu
|
11 Chancellors Walk, level 1, room 1.09
|
