Monash Macromolecular Crystallisation Platform

Overview of Services

Monash Biomolecular Crystallisation Platform is an automated platform for the high throughput crystallisation of biological macromolecules, operating on a fee-for-service model.

We provide Monash researchers with access to the newest nano-volume crystallisation and imaging technologies using state-of-the-art equipment:

• NT8 (Formulatrix) and

• Mosquito (TTP Labtech) - nano drop dispensing

• Formulator (Formulatrix) - building and dispensing customised optimisation screens using microfluidic technology

• 4 Rock Imagers (Formulatrix) - plate incubators/automated imaging systems

• 2 SONICC crystal detectors (Formulatrix) - using Second Harmonic Generation (SHG) and Ultraviolet Two-Photon Excited Fluorescence (UV-TPEF) for protein crystals detection in sitting drops and LCP

• Prometheus (NanoTemper) - nano DSF – protein thermal unfolding, chemical denaturation and aggregation

Our Services:

• Nano-volume crystallisation screening (vapour diffusion and LCP), followed by automated imaging with remote access to images

• Seeding and additive screening

• Custom screen design and dispensing for optimisation of crystallisation conditions.

• Protein stability testing by Differential Scanning Fluorimetry for crystallisation and other purposes (e.g. fragment/ small molecule binding assay)



Max Cryle


Geoffrey Kong



Location and hours of operation

Hours Location



11 Chancellors Walk

Monash University, Clayton Campus

Links and Resources


Name Role Phone Email Location
Geoffrey Kong

+61 3 990 59777
11 Chancellors Walk, level 1, room 1.09

Service list

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